In this case I was e-mailing my dear friend in Canada and it seems her e-mail address is not the same as when she e-mailed me her then current address in 2005. I wanted to get an update and this is what I got instead :
Hi. This is the qmail-send program at yahoo.com.
I'm afraid I wasn't able to deliver your message to the following addresses.
This is a permanent error; I've given up. Sorry it didn't work out.
Yup. Same error message. Tee!